Bob suggested this one when I mentioned the Play’n concept. A nazi hunter stumbles across a plot in South America where the remnants of the Reich are implementing a socio-genetic plan using “the world as [Joseph Mengele’s] laboratory”. This might give you a hint as to what they’re up to:
A definite lo-fi sci-fi movie. This kind of plot could easily have slid into B-movie schlock, but it’s a good deal smarter and subtler. It’s not good enough to be great, but not bad enough to be funny — which is why I expect I hadn’t heard of it.